卵巢低反应患者IVF-ET周期中AMH的检测价值及护理对策

Value of Measuring AMH Level and Nursing Strategies in Poor Ovarian Response Patients Undergoing IVF-ET

目的探讨卵巢低反应患者体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)周期中血清抗苗勒管激素(anti-mullerian hormone,AMH)检测的价值及护理对策。方法采用前瞻性研究方法分析南方医院妇产科生殖中心2014年1-12月接受IVF-ET治疗的112例不孕症女性患者的资料,ELISA方法检测血清AMH水平,偏相关方法分析血清AMH水平与IVF结局参数的关系;并行针对性心理疏导、用药宣教、手术护理、健康宣教等护理措施。结果卵巢低反应患者IVF-ET周期中血清AMH水平与获卵数和优质胚胎数均成正相关。结论血清AMH水平对预测卵巢低反应者IVF周期卵子和胚胎质量有指导意义,其中血清AMH水平下降提示卵巢低反应者IVF-ET周期卵子和胚胎质量发育欠佳。针对此类患者,应制定相应的护理对策,使患者在整个治疗周期中保持自然轻松的心理状态,积极配合治疗,并坦然接受治疗结果。

Objective To investigate the value of measuring AMH（anti-mullerian hormone） level and nursing strategies in poor ovarian response patients undergoing IVF-ET（in vitro fertilization and embryo transfer）. Methods A prospective method was used to analyze 112 patients with poor ovarian response undergoing IVF-ET treatment in Reproductive Center of Nanfang Hospital during the period from January to December in 2014. Serum AMH was detected with ELISA and partial correlation analysis was used to analyze the relationship between serum AMH level and IVF outcome. A targeted psychological counseling, drug education, intraoperative care, postoperative care as well as other nursing measures were conducted. Results A positive correlation was found between serum level of AMH and both the number of oocytes and good quality embryos in patients with poor ovarian response undergoing IVF-ET treatment. Conclusion Serum AMH level has predictive effects in patients with poor ovarian response during IVF- ET treatment. A decreased level of AMH is associated with poor quality of oocytes and embryos. For such patients, corresponding nursing strategies should he taken to ensure a relaxed mind state in order to achieve an active participation of treatment.