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局部晚期喉癌容积弧形调强放疗与固定野调强放疗的剂量学比较

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摘要 目的比较容积弧形调强放疗(volumetric modulated arc radiotherapy,VMAT)与固定野调强放疗(intensity-modulated radiotherapy,IMRT)技术在局部晚期喉癌应用中的剂量学差异。方法对11例局部晚期喉癌患者分别制定双弧VMAT与七野IMRT两组放疗计划。比较剂量体积参数,适形指数(CI),均匀指数(HI),计划设计时间,机器跳数(monitor unit,MU)和投照时间。结果高危靶区PTV1:VMAT的CI和HI明显优于IMRT(P<0.05)。低危靶区PTV2:VMAT的CI优于IMRT(P<0.05),HI与IMRT相当(P>0.05)。VMAT计划的脊髓(计划区)和脑干(计划区)的Dmax以及右侧腮腺的Dmean、V30Gy均低于IMRT(P<0.05),其他器官剂量两者相似(P>0.05)。VMAT计划设计时间较IMRT增多213%(P<0.05),MU与投照时间分别较IMRT减少64%与66%(P<0.05)。结论VMAT能达到较优的靶区剂量分布,保护部分危及器官,大幅减少MU及投照时间。
作者 陆佳扬 黄宝添 张基永 林珠 彭逊
机构地区 汕头大学医学院附属肿瘤医院放疗科
出处 《第三军医大学学报》 CAS CSCD 北大核心 2015年第18期1892-1895,共4页 Journal of Third Military Medical University
关键词 喉癌 容积弧形调强放疗 剂量学
分类号 R730.55 [医药卫生—肿瘤] R739.65 [医药卫生—肿瘤]
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参考文献12

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二级参考文献14

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共引文献12

第三军医大学学报
2015年 第18期

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