欣母沛治疗前置胎盘剖宫产产后出血的疗效分析

The efficacy of Hemabate in treatment of postpartum hemorrhage due to placenta previa in cesarean section

目的探讨欣母沛治疗前置胎盘剖宫产产后出血的临床疗效。方法选取2011年4月至2013年1月钟祥市妇幼保健计划生育服务中心收治的78例前置胎盘剖宫产患者的临床资料,根据不同治疗方法分为对照组和观察组,各39例。对照组采用注射缩宫素、舌下含服米索前列醇、子宫腔填塞纱条治疗,观察组在对照组基础上加用欣母沛治疗。观察比较两组患者的临床疗效。结果观察组治疗有效率92.3%(36/39)高于对照组的74.4%(29/39)(P<0.05);观察组产后2 h、24 h出血量少于对照组(P<0.05);两组患者产前及产后2 h血压、脉搏、血氧饱和度比较,差异均无统计学意义(P>0.05)。结论欣母沛治疗前置胎盘剖宫产产后出血疗效确切,能够有效降低出血量,且对机体影响小、安全性好。

Objective To investigate the efficacy of Hemabate in treatment of postpartum hemorrhage due to placenta previa in cesarean section. Methods Clinical data of 78 patients with placenta previa in cesarean section admitted in Maternal and Child Health Care and Family Planning Service Center of Zhongxiang City from Aug 2011 to Jan 2013 were chosen. All cases were divided into control group and observation group according to different therapies, with 39 cases in each group. The control group used oxytocin, sublingual misoprostol and uterine plug yarn. Observation group were added Hemabate based on the control group, the efficacy of two groups were observed and compared. Results The efficiency rate of the observation group [ 92.3 % （ 36/39 ） ] was significantly higher than the control group [ 74.4 % （ 29/39 ） ] （ P 〈 0.05 ）. The 2 h, 24 h postpartum hemorrhage in observation group was significantly less than the control group （ P 〈 0.05 ）. There was no significant difference in the prenatal and postnatal 2 h blood pressure, pulse and oxygen saturation between two groups （ P 〉 0.05 ）. Conclusion Hemabate has a good effect in treating postpartum hemorrhage due to placenta previa in cesarean section which can effectively reduce the amount of bleeding. It is safe and has little impact on the body.