I型NKT细胞在支气管哮喘发病机制中的作用

Role of type I natural killer T cells in the pathogenesis of bronchial asthma

支气管哮喘是一种慢性气道炎症性疾病，发病机制尚不完全明确。I型NKT细胞是一种独特的淋巴细胞亚群，通过产生多种细胞因子参与调节免疫反应。近年来I型NKT细胞在支气管哮喘发病机制中的作用备受关注，现就I型NKT细胞在支气管哮喘中的作用及机制作一综述。

Bronchial asthma is a chronic airways inflammatory disease,and the pathogenesis is not fully clear. Type I natural killer T cell, a unique subpopulation of T lymphocytes, has been shown to regulate immune responses through a massive production of a various cytokines. The role of type I natural killer T ceils in the pathogenesis of bronchial asthma has received much concern in recent years. Here is a review about the roles and mechanism of type I natural killer T cells in regulating the development of bronchial asthma.