野黄芩苷抗肿瘤作用机制

Anticancer mechanism of scutellarin

野黄芩苷（SC）是一种具有抑制自由基生成、抗炎、心肌保护和抗病毒等多种药理活性的中药提取物。近年研究表明SC对多种肿瘤的生长具有抑制作用，是一种潜在的抗肿瘤药物。其抗肿瘤机制主要有诱导细胞凋亡、阻遏细胞周期、增强黏附力及抗侵袭、逆转肿瘤多药耐药、抑制肿瘤血管新生等。

Scutellarin （SC） , a botanical extract, possesses a variety of suppressing free radical gener- ation, anti-inflammatory, cardioprotection and anti-virus activity. Recently, many studies show that SC has inhibitory effects on the growth of many tumors and is a kind of potential anti-tumor drug. Its anti-tumor mecha- nisms mainly include inducing apoptosis, arresting cell cycle, enhancing the adhesion between cells, inhibiting tumor invasion, reversing multidrug resistance, anti-angiogenesis and so on.