腹腔镜胆囊切除术治疗胆囊癌的疗效和安全性分析

Efficacy and Safety of Laparoscopic Cholecystectomy on Treatment of Gallbladder Carcinoma

目的对比腹腔镜下胆囊切除术与胆囊癌根治手术治疗胆囊癌的临床疗效。方法筛选2010年2月至2015年5月我院收治的胆囊癌患者70例为研究对象。采用随机数表法将其分为观察组与对照组,每组35例。对照组常规开放胆囊癌根治术,观察组腹腔镜胆囊切除术,比较患者术后并发症发生情况及一般临床指标,并统计两组患者术后1年、5年生存率。结果观察组术中出血量、术后排气时间、手术用时、消化功能恢复时间、住院时间等均低于对照组,并且观察组术后并发症、不良反应发生率明显低于对照组(P<0.05);观察组患者术后复发率高于对照组,但患者术后5年生存率高于对照组(P<0.05)。结论腹腔镜胆囊切除术治疗胆囊癌疗效确切,并且手术对患者损伤低,术后并发症发生率较低,手术安全性高,患者生存率得到有效提高,具有临床应用及推广价值。

Objective To compare the clinical effect of laparoscopic cholecystectomy and gallbladder carcinoma on treatment of gallbladder carcinoma. Methods 70 cases of gallbladder cancer patients admitted in our hospital from February 2010 to May 2015 were selected as the research object. They were divided into observation group and control group by using random number table method, with 35 cases in each group, control group underwent conventional open radical resection of gallbladder carcinoma, observation group underwent laparoscopic cholecystectomy, compared two groups＇ postoperative complications and clinical indexes. Recorded two groups＇ survival rate after 1 year and 5 years. Results Observation group＇s bleeding, postoperative exhaust time, surgery, digestive function recovery time, hospitalization time were lower than control group, observation group＇s postoperative complications and adverse reactions occurred were significantly lower than control group（P〈 0.05）; observation group＇s postoperative recurrence rate was higher than control group, but postoperative 5 years survival rate was higher than control group（P 〈0.05）. Conclusion Laparoscopic cholecystectomy surgery has exact effect on treatment of gallbladder cancer exactly, it has low injury and low rate of postoperative complications. It is worthy of application and popularization with its high operation safety and high survival rate.