67例梅毒患者5种检测方法的研究探讨

Study on 5 Methods for Detection of 67 Cases of Syphilis

目的探讨5种检测方法在梅毒诊断中的作用。方法对67例梅毒患者,分别用RPR、TRUST、胶体金法、TP-ELISA、TPPA等方法进行检测。结果与TPPA法相比较,RPR法、TRUST法的敏感性低,有显著性差异;胶体金法与ELISA法的敏感性较高,与TPPA相近,不存在显著性差异。结论 RPR法与TRUST法,不适合于梅毒的早期筛查;而梅毒螺旋体抗体胶体金法或TP-ELISA法的敏感性、特异性较好,且操作上比TPPA法简单,适合于梅毒的早期筛查。

Objective To explore the effect of 5 kinds of detection methods in diagnosis of syphilis. Methods In 67 cases of syphilis patients, respectively RPR, TRUST, colloidal gold method, TP-ELISA, TPPA for testing. Results Compared with the TPPA method, RPR method, TRUST method, the sensitivity is low, there is a significant difference ;The colloidal gold method and ELISA method, the sensitivity is high,similar to TPPA, there is no significant difference. Conclusions RPR method and TRUST method, is not suitable for early syphilis screening; While the sensitivity, specificity of the colloidal gold method and ELISA method is good, and the operation is simpler than the TPPA method, is suitable for early syphilis screening.