镁极化液与1,6-二磷酸果糖治疗射血分数正常心力衰竭的临床效果

Clinical effect of Mg-GIK combined with FDP treating heart failure with normal ejection fraction

目的探讨镁极化液（Mg-GIK）与1,6-二磷酸果糖（FDP）治疗射血分数正常心力衰竭（HFNEF）的临床效果。方法选取2009年6月~2013年12月在我院住院的HFNEF患者90例,随机分为两组,对照组给予利尿剂、ACEI、硝酸酯类等药物常规治疗;治疗组在常规治疗基础上加用Mg-GIK与FDP治疗,10 d为1个疗程。结果治疗组与对照组心功能改善总有效率分别为86.7%、62.2%,两组比较,差异有统计学意义（P〈0.05）。随访3个月,两组再住院率比较差异无统计学意义（P〉0.05）。结论 Mg-GIK与FDP治疗HFNEF能明显改善患者的心功能。

Objective To explore the clinical effect of Mg-GIK combined with FDP treating heart failure with normal ejection fraction（HFNEF）. Methods 90 patients with HFNEF hospitalized in our hospital from June 2009 to December2013 were selected.Patients were randomly divided into two groups.Control group was given routine drugs therapy such as diuretic,ACEI and nitrate esters.On the basis of control group,treatment group was given Mg-GIK combined with FDP,and a course of treatment was 10 days. Results The total rate of heart function improvement in treatment group and control group was 86.7% and 62.2% respectively,and the difference was statistical significance（P〈0.05）.Patients were followed-up for 3 months,the rehospitalization rate between two groups had no statistical difference（P 〉0.05）.Conclusion Mg-GIK combined with FDP treating HFNEF can significantly improve heart function of patients.