经颅磁刺激治疗偏头痛急性发作期的疗效观察

Observation of curative effect by transcranial magnetic stimulation in the treatment of acuteoutbreak period of migraine

目的比较经颅磁刺激在治疗偏头痛急性发作期方面的疗效。方法 48例偏头痛急性发作期患者随机分为治疗组和对照组,各24例。两组均给予常规药物治疗,治疗组加用经颅磁刺激治疗。观察两组患者治疗后10 d及30 d的头痛程度及头痛次数方面的变化。结果治疗后10 d两组患者头痛程度均减轻,治疗组头痛程度明显低于对照组,差异有统计学意义(t=-3.275,P=0.002<0.05);治疗后30 d,两组患者头痛程度及头痛次数较治疗前减少,差异均有统计学意义(t=-3.66,P=0.01<0.05;t=-2.038,P=0.047<0.05)。结论经颅磁刺激治疗偏头痛急性发作期安全有效,值得临床推广应用。

Objective To compare curative effect by transcranial magnetic stimulation in the treatment of acute-outbreak period of migraine. Methods A total of 48 patients with acute-outbreak period of migraine were randomly divided into treatment group and control group, and each group contained 24 cases. Both groups received conventional drug therapy, and the treatment group received additional transcranial magnetic stimulation treatment. Changes of headache seriousness and frequency in the two groups were observed in 10 d and 30 d after treatment. Results Both groups had relieved headache in 10 d after treatment, and the treatment group had much lower headache seriousness than the control group. Their difference had statistical significance（t=-3.275, P=0.0020.05）. In 30 d after treatment, both groups had decreased headache seriousness and frequency, comparing with those before treatment. Their differences all had statistical significance（t=-3.66, P=0.010.05; t=-2.038, P=0.0470.05）. Conclusion Implement of transcranial magnetic stimulation is safe and effective in treating acute-outbreak period of migraine, and it is worthy of clinical promotion and application.