河南某农村中老年女性人群高甘油三酯腰围与2型糖尿病的关系

Association between hypertriglyceridemia-waist and type 2 diabetes mellitus among the middle and elderly females in a rural area of Henan Province

目的：：分析河南某农村中老年女性人群高甘油三酯腰围（HTGW）与2型糖尿病（T2DM）的关系。方法：采用整群抽样的方法调查河南某镇中老年女性人群的人口统计学特征、行为危险因素,并进行人体测量及空腹脂质谱和血糖检测。评估各危险因素与 T2DM 的关系。结果：共调查4651人,其中 T2DM 患者429人（患病率9.22%）,HTGW 1642人（患病率35.30%）。单因素分析显示腰围异常、糖尿病家族史、年龄和 TG 〉1.7 mmol/ L是 T2DM 的主要危险因素,OR（95% CI）分别是2.77（2.11～3.64）、2.77（2.05～3.75）、2.14（1.74～2.62）和2.16（1.76～2.64）,中度和重度体力活动可降低 T2DM 的患病风险,OR（95% CI）分别是0.14（0.03～0.57）和0.54（0.43～0.68）（P 均〈0.05）。调整其他危险因素后 HTGW 与 T2DM 的 OR（95% CI）为4.43（3.06～6.41）（P 〈0.05）。结论：HTGW 增加河南农村中老年女性人群 T2DM 的患病风险,可以考虑作为 T2DM 的筛检工具。

Aim： To investigate the association of hypertriglyceridemia-waist（HTGW） with type 2 diabetes mellitus （T2DM） among the middle and elderly females in a rural area of Henan Province. Methods： With a clustered sampling method, 4 651 middle and elderly females were investigated by collecting data regarding demographic characteristics, be-havioral risk factors, anthropometric measurements, and fasting plasma lipid profiles and glucose. The odds ratio of each risk factor for T2DM was evaluated. Results： A total of 4 651 females were investigated,among whom, 429 females （9. 22% ） suffered from T2DM,and 1 642 females（35. 30% ） suffered from HTGW. The univariate analysis indicated that elevated waist circumference,family history of diabetes,age,and hypertriglyceridemia were main risk factors,and the OR （95% CI） was 2. 77（2. 11 - 3. 64）,2. 77（2. 05 - 3. 75）,2. 14（1. 74 - 2. 63）,and 2. 16（1. 76 - 2. 64）,respectively. Moderate and high physical activities were the protection factors for T2DM, and the OR（95% CI） was 0. 14（0. 03 - 0. 57） and 0. 54（0. 43 - 0. 68）. After adjustment for age, education level, marital status, smoking, drinking, BMI, blood pres-sure,physical activity, and family history of diabetes, HTGW was significantly associated with T2DM, and the OR（95%CI） was 4. 43（3. 06 - 6. 41）. Conclusion： HTGW is significantly associated with an increased risk of T2DM among the middle and elderly females in a rural area of Henan Province,and it might be a useful screening tool for T2DM.