摘要
目的:探讨胰岛素强化治疗方案对妊娠期糖尿病(GDM)患者及胎儿的影响。方法:将70例妊娠期糖尿病患者按照随机数字表法分为2组,其中对照组35例用预混人胰岛素类进行常规治疗;观察组35例每天速效胰岛素3次注射加基础胰岛素1次注射进行强化治疗;对比分析两组患者治疗后血糖控制水平、胰岛素抵抗(HOMA-IR)程度、胰岛素分泌指数(HOMA-β)变化、妊娠合并症及新生儿合并症的发生率等。结果:观察组的患者血糖控制效果更佳,显著降低母婴并发症(P<0.01),胰岛素抵抗程度与胰岛素分泌功能均有所改善(P<0.05)。结论:胰岛素强化治疗妊娠期糖尿病可以减少母婴并发症的同时,可以在一定程度上改善患者的胰岛功能水平。
Objective: To investigate the effect of intensive insulin therapy on patients with gestational diabetes mellitus( GDM). Methods: 70 cases of pregnancy with gestational diabetes were divided into 2 groups according to the random number table. The control group( n = 35) pre mixed insulin class conventional therapy; observation group( 35 cases) every available insulin three times injection plus basal insulin 1 injection intensive treatment; after treatment,the patients in the two groups compared with control of blood glucose levels,insulin resistance( HOMA- IR),insulin secretion index( HOMA- β) changes,pregnancy complications and neonatal complications occurrence rate. Results: in the observation group,the patients blood glucose control effect is better,significantly reduce the complications of mothers and infants(P〈0. 01),the degree of insulin resistance and insulin secretion were somewhat improved(P〈0. 05). Conclusion: insulin intensive treatment of gestational diabetes can reduce maternal and infant complications at the same time,to a certain extent,improve the level of pancreatic islet function.
出处
《江西中医药大学学报》
2015年第4期33-34,44,共3页
Journal of Jiangxi University of Chinese Medicine
基金
广东省河源市科技局项目
关键词
胰岛素泵
2型糖尿病合并妊娠
并发症
Insulin Pump
Type 2 Diabetes Mellitus Combined with Pregnancy
Complication