923例新的和严重的药品不良反应报告分析

The Report Analysis of 923 Cases of New and Serious Adverse Drug

目的:分析赣州市新的和严重的药品不良反应报告情况,为临床合理用药提供参考。方法:对赣州市2013年上报国家药品不良反应监测平台的923例新的和严重的不良反应病例进行回顾性研究分析。结果:引起新的和严重的药品不良反应涉及的药品以抗感染药物最多,以注射剂为主要剂型,以注射给药为主要途径,表现主要为全身性损害、呼吸系统损害和胃肠系统损害。结论:在临床用药中应重点关注抗感染药和注射剂型,加强合理用药,减少和避免不良反应的发生。

Objective： To analyze the reporting of new and severe adverse drug reaction in Ganzhou city and so as to provide a scientific basis for clinical rational drug use. Methods： Have a retrospective analysis in 923 new and severe adverse drug reports,which were reported to the national adverse drug reaction monitoring platform by the Institute for Food and Drug Control of Ganzhou in 2013. Results： Most of these new and severe adverse drug reactions were caused by anti- infection drugs. They take injection as the main dosage form and take injection as the main route of administration,and mostly caused systemic damage、respiratory system injury and the gastrointestinal system damage. Conclusion： Anti- infection drugs and injection should be given specific focus in clinical to reduce and avoid the occurrence of adverse reactions.