期刊文献+

骨髓基质干细胞治疗股骨头坏死的回顾与评价 被引量:4

A review of bone marrow stromal stem cell for treatment of osteonecrosis of the femoral head
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摘要 股骨头坏死是一种常见的髋部病变,常导致髋关节功能障碍。早期发现和早期治疗有助于改善预后。目前对股骨头坏死的治疗手段众多,但缺乏令人满意的早期治疗手段。干细胞治疗早期股骨头坏死是近年来值得关注的一个重要研究方向。本文回顾了骨髓基质干细胞治疗股骨头坏死的相关研究进展并作相应评价。 Osteonecrosis of the femoral head is a common disease which often leads to hip dysfunction. Diagnosis and treatment in the early stage play an important role in improving prognosis. Currently, there are different kinds of treatment for the disease, but there are still no satisfactory means for early treatment. Stem cell treatment is a remarkable research direction for osteonecrosis of the femoral head in the early stage. This article reviewed and evaluated the progress in related researches.
出处 《临床外科杂志》 2015年第8期627-629,共3页 Journal of Clinical Surgery
基金 国家自然科学基金资助项目(81271969)
关键词 骨髓基质干细胞 股骨头坏死 marrow stem cells osteonecrosis of the femoral head
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  • 1Zalavras CG, Lieberman JR. Osteonecrosis of the femoral head:evaluation and treat- ment[J]. J Am Acad Orthop Surg,2014, 22(7 ) :455-464.
  • 2Hernigou P, Flouzat-Lachaniette CH, Del- arnbre J, et al. Osteoneeresis repair with bone marrow cell therapies: State of the clinical art[ J]. Bone,2014,70 ( 1 ) : 102- 109.
  • 3Assouline-Dayan Y, Chang C, Greenspan A,et al. Pathogenesis and natural history of osteonecrosis [ J ]. Semin Arthritis Rheum,2002,32 (2) :94-124.
  • 4Lee JS, Roh HL, Kim CH, et al. Altera- tions in the differentiation ability of mes- enehymal stem cells in patients with non- traumatic osteonecresis of the femoral head: comparative analysis according to the risk factor [ J ]. J Orthop Res, 2006, 24(4) :604-609.
  • 5Feng Y, Yang SH, Xiao B J, et al. De- creased in the number and function of circulation endothelial progenitor cells in patients with avascular necrosis of the femoral head [ J]. Bone, 2010,46 ( 1 ) : 32-40.
  • 6Grayson WL, Bunnell BA, Martin E, et al. Stromal cells and stem cells in clinical bone regeneration [ J ]. Nat Rev Endocri- nol,2015,1 t ( 3 ) : 140-150.
  • 7Jiang Y, Jaliagirdar BN, Reinhard RL, et al. Pluripotency of mesenehymal stem ceils derived from adult marrow [ J ]. Na- ture, 2002,418 ( 6893 ) :41-49.
  • 8Raehwitz L, Eden L, Reppenhagen S, et al. Stem cell- and growth factor- based regenerative therapies for avaseular nec- rosis of the femoral head [ J ]. Stem Cell Res Ther,2012,3 ( 1 ) : 1-9.
  • 9Mont MA, Jones LC, Einhorn TA, et al. Osteoneerosis of the femoral head. Poten- tial treatment with growth and differentia- tion factors [ J ]. Clin Orthop Relat Res, 1998,10(335S) :314-335.
  • 10Jorgensen NR, Henriksen Z, Sorensen OH, et al. Dexamethasone, BMP-2, and 1, 23-dihydroxyvitamin D enhance a more differentiated osteoblast phenotype: validation of an in vitro model for human bone marrow-derived primary osteoblasts[ J ]. Steroids,2004,69 ( 4 ) :219 -226.

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  • 1喻爱喜,余国荣,邓凯,陶圣祥,潘振宇,张建华,宋九宏.封闭负压吸引联合组织瓣移植治疗严重感染性骨外露[J].中华显微外科杂志,2006,29(3):219-220. 被引量:179
  • 2陶圣祥,喻爱喜,余国荣,宋九宏,邓凯,祝少搏,张奕,郑晓晖.VSD在伴严重软组织损伤的手掌离断再植术中的应用[J].解剖与临床,2007,12(6):415-416. 被引量:51
  • 3Lindstedt S, Malmsjo M, Sjogren J, et al. Impact of different topical negative pressure levels on myocardial microvascular blood flow [ J ]. Cardiovasc Revasc Mcd ,2008,9 ( 5 ) :29-35.
  • 4Reddix R.J, Leng XI, Woodall J, et al. The effect of incisional negative pressure therapy on wound complieations after ace-tabular fracture sur- gery [ J ]. J Surg Orthop Adv,2010,19 ( 3 ) :91-97.
  • 5Murali TS, Kavitha S, Spoorthi J, et al. Characteristics of microbial drug resistance and its correlates in ehronic diabetic fo~~t ulcer infec- tions[J].J Med Microbiol,2014,63 ( 5 ) : 1377-1385.
  • 6Hunsicker LG. Emerging trends for prevention and treatment of" diabet- ic nephropathy:blockade of the RAAS and BP control [ J ]. J Manag Care Pharm,2004,10(5) :12-17.
  • 7Narita T, Kakei M, Ito S. Aggressive antihypertensive treatment and se- rum lipid lowering therapy are necessary to prevent deterioration of the renal function even in elderly type 2 diabetic patients with persistent albumjnurj a [ J ]. Gerontology, 2002,48 ( 5 ) : 302 -308.
  • 8Younan G, Ogawa R, Ramirez M, et al. Analysis of nerve and neu- ropeptide patterns in vacuum-assisted closure-treated diabetic murine wounds[ J]. Plast Reconstr Surg,2010,126 ( 1 ) :87-96.
  • 9李平运,曹建博.股骨头坏死的病因及发病机制[J].中国医刊,2010,45(2):18-20. 被引量:9
  • 10李刚,王均玉.股骨头坏死的中医认识与研究现状[J].山西中医,2010(5):52-54. 被引量:24

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