低出生体重儿低血糖发生、早期干预及后期随访的临床研究

Clinical Studies of Occurrence Early Intervention and Late Follow-u Pof Low Birth Weight Infants Hypoglycemia

目的:了解低出生体重儿低血糖发生、早期干预降低低血糖脑损伤及相关随访情况。方法:收集2009年5月至2013年5月收治的足月小样儿73例及早产儿91例。其中足月小样儿组有17例发生低血糖,早产儿组41例发生低血糖。比较两组在出生时间、出生体重及胎龄等方面对血糖影响。结果:164例出生低体重儿中共有58例患有低血糖。其两组在出生时间、出生体重、血糖无显著差异,胎龄有显著性差异。新生儿低血糖的出现与出生体重有相关性,出现低血糖的新生儿与血糖水平正常的新生儿出生体重有统计学上的显著性差异。经过早期干预在核磁和脑电图未发现脑损伤情况。随访发现足月儿小样儿组有2例发生脑损伤。早产儿组有1例发生脑损伤。结论:影像学上的阴性结果并不意味着患儿的远期预后不受影响。

Objective： To investigate the low birth weight infants hypoglycemia,hypoglycemia early intervention to reduce brain damage and related follow-up cases.Methods：From May 2009 to May 2013 were treated 73 cases of full-term small for gestational age and 91 cases of preterm infants.Which the term small for gestational age group 17 cases of hypoglycemia,hypoglyc emia group of 41 patients in preterm infants.Comparison of the two groups at the time of birth,birth weight and gestational age and other aspects of the impact on blood sugar.Results： 164 cases of low birth weight total of 58 cases of infants suffering from low blood sugar.The two groups in the time of its birth,birth weight,blood glucose was no significant difference,there was a significant difference in gestational age.The emergence of neonatal hypoglycemia correlated with birth weight,neonatal hypoglycemia and blood glucose levels normal birth weight newborns have significant difference statistically.Early intervention is not found after brain injury in NMR and EEG.Term follow-up found that infants small for gestational age group,2 cases of brain damage.Preterm infants group1 patients had brain damage.Conclusion： On the negative results of imaging does not mean the forward prognosis in children affected.