某医院多重耐药菌感染目标性监测和干预措施

The goal surveillance and intervention measure of multiple drug infection in a hospital

目的了解多重耐药菌(MDRO)感染分布,以便采取综合性干预措施。方法采用目标性监测方法,对某三甲医院住院患者送检的病原学标本检验结果进行回顾性分析。结果 2013年度,从该医院住院患者送检病原学标本中内共检出病原菌1 173株,含多重耐药菌216株,检出率为18.41%;2014年度共检出病原菌1 083株,含多重耐药菌293株,检出率27.05%。检出的MDRO主要是大肠埃希菌、肺炎克雷伯菌、金黄色葡萄球菌和鲍曼不动杆菌。MDRO感染患者主要分布在综合重症监护病房(ICU)、神经外科ICU和泌尿外科。结论该医院住院患者多重耐药菌感染比例较高,主要集中在ICU,应采取严格消毒隔离、实时监测和控制抗菌药物的应用等综合措施加以防控。

Objective To know the distribution of multiple drug resistant bacteria （MDRO） infection, so as to take com- prehensive intervention measures. Methods Targeted monitoning methods were used for retrospectively analyze with the results of inpatient＇ s etiological samples of a hospital. Results 1 173 strains of pathogenic bacteria were detected in pathogen specimen of inpatients in our hospital in 2013, among them 216 strains were multiple drug resistant bacteria （ 18. 41% ）, 1 083 strains were detected in 2014, among them 293 strains were multiple drug resistant bacteria（27.05% ）. Escherichia coli , Klebsiella pneumonia, Staphylococcus aureus and Acinetobacter baumannii were the majority, mainly con- centrated in intensive care unit （ ICU ）, neurosurgical intensive care unit, and department of neurosurgical surgery. Con- clusion The nosocomial infection rate is high in hospitalized patients in our hospital, and mostly concentrated in ICU. Comprehensive measures including strict disinfection and isolation, real - time monitoring and control of the use of antibac- terial drugs should be adopted for prevention and control.