Barrett食管与结直肠息肉的相关性

Correlation between Barrett's esophagus and colorectal polyps

目的:探讨Barrett食管与结直肠息肉的相关性.方法:收集Barrett食管组41例,对照组176例,比较两组中结直肠息肉的发生率,息肉的病理类型及息肉发生部位.结果:Barrett食管组中息肉发生率为41.5%,高于对照组的25.6%,二组之间差异有统计学意义(P=0.042).两组中炎性息肉及增生性息肉的发生率差异无统计学意义(P=0.32,P=0.18).但Barrett食管组中腺瘤性息肉发生率显著高于对照组(P=0.008).两组中息肉发生部位无明显差异.多因素Logistic回归分析显示Barrett食管是结直肠息肉的独立相关因素(OR=2.397,95%CI:1.146-5.013,P=0.020).结论:Barrett食管与结直肠息肉发生相关,对Barrett食管患者应重视结直肠息肉筛查和监视.

AIM： To explore the correlation between Barrett＇s esophagus and colorectal polyps. METHODS： A total of 41 patients with Barrett＇s esophagus and 176 controls were enrolled in the study. The incidence, pathological type and location of colorectal polyps were compared. RESULTS： The incidence of polyps in patients with Barrett＇s esophagus was 41.5%, whichwas signif icantly higher than that of the control group（25.6%）（P = 0.042）. The incidence of adenomatous polyps in patients with Barrett＇s esophagus was also signif icantly higher than that of the control group（P = 0.008）, although there was no signif icant difference in the incidence of hyperplastic polyps and inflammatory polyps.The location of colorectal polyps showed no significant difference between the two groups.Logistic multivariate regression analysis revealed that Barrett＇s esophagus was an independent risk factor for colorectal polyps（OR = 2.397, 95%CI：1.146-5.013, P = 0.020）.CONCLUSION： Patients with Barrett＇s esophagus have a higher incidence of colorectal polyps.Therefore, the screening and surveillance of colorectal polyps should be enhanced in patients with Barrett＇s esophagus.