期刊文献+

非甾体类抗炎药致老年人上消化道出血的临床分析 被引量:15

下载PDF
导出
摘要 目的分析老年人服用非甾体类抗炎药(NSAIDs)致上消化道出血的临床特征。方法回顾性分析92例60岁以上消化性溃疡出血住院患者的临床资料,依据出血前10 d内是否服用过NSAIDs将患者分为NSAIDs组(40例)和非NSAIDs组(52例),并对两组患者的临床资料进行分析比较。结果在性别方面,NSAIDs组与非NSAIDs组比较差异无统计学意义(P>0.05);在心脑血管病史、血红蛋白含量、消化道溃疡等方面NSAIDs组与非NSAIDs组比较差异有统计学意义(P<0.05)。结论与非NSAIDs相比,NSAIDs组老年人更易合并心血管疾病,Hb较低,胃溃疡较常见、糜烂少见。NSAIDs服用时间越长,形成溃疡出血的几率越高。
出处 《安徽医学》 2015年第7期869-871,共3页 Anhui Medical Journal
  • 相关文献

参考文献12

二级参考文献51

共引文献119

同被引文献121

  • 1赵建秋,卢向东,张志广.老年上消化道出血后诱发急性心肌梗塞31例临床分析[J].医学信息(医学与计算机应用),2016,29(32):307-307. 被引量:2
  • 2窦裁凤,刘元元,赵翀.上消化道出血病因构成、出血量估计、病因趋势及相关因素[J].中国老年学杂志,2014,34(7):1815-1816. 被引量:22
  • 3Friedewald VE, Bennett JS, Christo JP, et al. AJC Editor's consensus:selective and nonselective nonsteroidal anti-inflammatory drugsand cardiovascular risk. American Journal of Cardiology, 2010,106(6):873-884.
  • 4Fashner J, Gitu AC. Diagnosis and Treatment of Peptic Ulcer Disease and H. pylori Infection [ J ]. Am Fam Physician, 2015,91 ( 4 ) : 236- 242.
  • 5Lamberts M, Lip GY, Hansen ML, et al. Relation of nonsteroidal anti- inflammatory drugs to serious bleeding and thromboembolism risk in patients with atrial fibrillation receiving antithrombotic therapy:a na- tionwide cohort study [ J ]. Ann Intern Med, 2014, 161 ( 10 ) : 690- 698.
  • 6Wang BY, Zhang J, Wang JL, etal. Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancer[ J]. J Exp Clin Cancer Res,2015,34 ( 1 ) : 85.
  • 7Qi Q,Wang R, Liu L,et al. Comparative effectiveness and tolerability of esomeprazole and omeprazole in gastro-esophageal reflux disease : A systematic review and meta-analysis[ J ]. Int J Clin Pharmacol Ther, 2015,53(10) :803-810.
  • 8Zullo A, Ridola L, Francesco VD, et al. High-dose esomeprazole and amoxicillin dual therapy for first-line Helicobacter pylori eradication : a proof of concept study [ J ]. Ann Gastroenterol, 2015,28 ( 4 ) : 448- 451.
  • 9Georgopoulos SD, Papastergiou V, Karatapanis S. Treatment of Heli-cobacter Pylori ilffection: optimization strategies in a high resistance era[ J ]. Expert Opin Phammcother,2015,16 ( 15 ) :2307-2317.
  • 10张彭,王孟春.非甾体抗炎药致胃肠道黏膜损伤的研究进展[J].实用药物与临床,2008,11(6):378-380. 被引量:13

引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部