2009—20l3年绵阳市预防接种异常反应监测结果

Surveillance results of AEFI in Mianyang City from 2009-2013

目的 了解四川省绵阳市预防接种异常反应（AEFI）的发生特征,评价AEFI监测系统运转情况,分析其影响因素,提高监测的敏感性.方法 利用excel对2009-2013年绵阳市AEFI数据进行描述性分析.结果 该市共使用疫苗44种,接种6 632 472剂次,报告发生AEFI的共26种疫苗548例,报告发生率为8.26/10万剂.以一般反应为主,占报告总数的77.56％;无细胞百白破疫苗（DTaP）反应人数最多,占报告总数的29.38％.AEFI的发生和接种针次与年龄有关,0～2岁病例数最多,反应时间主要集中在当日和次日,占报告总数的81.57％.临床诊断主要以发热、红肿、硬结和过敏性皮疹最为多见,占总报告数的81.21％.结论 该市AEFI主要发生于DTaP,以一般反应为主;近年来该市AEFI监测敏感性不断提高.

[Objective]To understand the incidence features of Adverse Events Following Immunization （AEFI）, to evaluate the operation of AEFI surveillance system, to analyze its influencing factors, and improve sensitivity of monitoring. [Methods]Excel was used to descriptively analyzed the AEFI data of Mianyang City from 2009-2013.[Results]A total of 44 kinds of vaccine were used in Mianyang City, with 6 632 472 times of vaccination, Among which 548 AEFI eases were reported, involving 26 kinds of vaccine, the reported incidence rate was 8.26/100 000. Most AEFI cases had general reaction, accounting for 77.56%, 29.38% induced by DTaP vaccine. The occurrence of AEFI was related with the times of vaccination and age, most cases were 0-2 years old children. The reaction time concentrated in the day and the next day, accounting for 81.57%. The most symptoms were fever, redness, induration, and allergic rashes, accounting for 81.21%.[Conclusion]The occurrence of AEFI is mainly caused by DTaP vaccine, with the general reaction. The sensitivity of AEFI surveillance has been improved in recent years in this city.