辛癸基葡糖苷辅助提取暴马丁香中橄榄苦苷的工艺优化

Optimization of APG0810-assisted Extraction of Oleuropein from Syringa reticulata Branch

橄榄苦苷是我国重要林下经济植物——暴马丁香的主要活性成分之一,具有较好的药用价值。结合橄榄苦苷提取过程中存在的问题,通过单因素试验和响应面试验,得到辛癸基葡糖苷(APG0810)辅助提取暴马丁香树枝中橄榄苦苷的最佳提取工艺条件为:提取溶剂为80%的乙醇溶液中添加0.5%的APG0810,超声提取温度55℃,料液比为1∶20 g/m L,提取时间为46 min,此工艺条件下橄榄苦苷得率为4.41±0.11%。提取暴马丁香中橄榄苦苷的工艺优化研究既可以为医药、化妆品等领域提供新的植物资源,又能为暴马丁香资源的精深加工利用提供技术支持。

Oleuropein is one of the main active components of the economic plant,Syringa reticulata. Oleuropein has the following main activities： antioxidant, anti-inflammatory, anti atherosclerosis, anti-cancer, antiviral activity and the protec- tion of cardiac damage, lowering blood glucose and blood lipid, hence it has been widely used in medicine, cosmetics and other fields. In view of the problems existing in the process of oleuropein extraction,the optimization of APC,0810-assis- ted extraction of oleuropoin from S. reticulata branch was carried out by single factor tests and response surface tests. The optimal extraction conditions were：extraction solvent was 80% ethanol solution with 0.5% APG0810, ultrasonic temper- ature was 55 ℃ the ratio of solid to liquid was 1：20 g/mL, extraction time was 46 rain. Under these conditions, the yield of oleuropein was 4.41± 0. 11%. This study provided technical support for deep processing of Syr/nga resources.