输血前不规则抗体危急值检测的临床价值

Significance and Value of the Iirregular Antibodies Detection Befor the Transfusion

目的研究输血前不规则抗体危急值检测的意义,以便总结不规则抗体危急值检测在输血前的价值。方法选取我院自2012年12月~2014年12月住院需输血的患者11249例,对其进行不规则抗体筛查,总结不规则抗体危急值检测在输血前的意义。结果本组11249例患者中,筛查出不规则抗体危急值阳性36例,其中男11例,女25例,输血史患者8例,妊娠史患者19例,既有妊娠史,也有输血史患者7例,既无妊娠史,也无输血史患者2例,男女的抗E、抗D、抗Ec、抗M、抗Jkb、其他的阳性率比较,差异无统计学意义（P〉0.05）。2012年1月~2012年12月不规则危急值阳性率0.24%,2013年1月~2013年12月不规则危急值阳性率2.78%,2014年1月~2014年12月不规则危急值阳性率0.40%,2012年、2013年及2014年不规则危急值阳性率比较,差异无统计学意义（P〉0.05）。结论确保所有患者在输血前进行不规则抗体检测,并且设立危急值报告制度对因不规则抗体引起的输血反应有较好的预防作用。

Objective To study the irregular antibody detection significance values before transfusion,in order to summarize the value of irregular antibody detection before blood transfusion.Methods Selected 11249 cases in our hospital from 2012 December to 2014 December hospitalization required blood transfusion patients,irregular antibody screening on the summary of irregular antibodies detection of the values before transfusion significance. ResultsIn this group,11249 patients, irregular antibody screening of critical value was positive in 36 cases,including male 11 cases,female 25 cases, 8 cases of blood transfusion patients,19 cases of in patients with a history of pregnancy,both pregnancy history,there are 7 cases of patients with a history of blood transfusion,no history of pregnancy,no history of blood transfusion in 2 cases comparison of male and female patients,anti E,anti D,anti Ec,anti M,anti Jkb and other positive rate,no significant difference（P〉0.05）. From 2012 January to 2012 December the irregular critical values the positive rate was 0.24%,from 2013 January to 2013 December the irregular critical values the positive rate was 2.78%,from 2014 January to 2014 December the irregular critical values the positive rate was 0.40%,in 2012,2013 and 2014 irregular critical value positive rate comparison,the difference was not statisticaly significant（P〉0.05）.Conclusion To ensure that al patients with irregular antibody detection before transfusion,and the establishment of critical value report system have better prevention effect of transfusion reaction caused by irregular antibody.