超声弹性成像对肝炎后肝纤维化患者诊断价值

Diagnostic Value of Ultrasound Elastography in Evaluating Hepatic Fibrosis Secondary to Hepatitis

目的探讨超声弹性成像对肝炎后肝纤维化患者诊断价值。方法通过对病理分级和超声弹性成像评分、应变比进行比较,探讨超声弹性成像对肝炎后肝纤维化患者诊断价值。结果 60例患者的肝纤维化病理分期结果 :S0期18例,S1期17例,S2期12例,S3期6例,S4期7例;超声弹性成像评分结果 :0分17例,1分16例,2分13例,3分5例,4分9例。病理结果 :肝纤维化42例,无肝纤维化18例;超声弹性成像评分结果 :肝纤维化43例,无肝纤维化17例。超声弹性成像灵敏度为92.9%,特异度为77.8%。S0期应变比为(1.61±0.42),S1期应变比为(1.37±0.33),S2期应变比为(0.98±0.23),S3期应变比为(0.74±0.27),S4期应变比为(0.59±0.36)。肝纤维化各期与S0期的组间差异有统计学意义(P<0.05)。结论超声弹性成像技术无创、可重复,对肝纤维化程度具有较高的诊断价值。

Objective To investigate the diagnostic value of ultrasound elastography in evaluating hepatic fibrosis secondary to hepatitis.MethodsComparing pathological examination,ultrasound elastography score and strain ratio.ResultsAmong 60 patients,18 were pathologicaly staged at S0 of hepatic fibrosis,17 at S1 stage,12 at S2 stage,6 at S3 stage,7 at S4 stage;17 were score 0 by ultrasound elastography,16 cases scored 1,13 cases scored 2,5 cases scored 3,9 cases scored 4. As revealed by pathological results,42 cases had hepatic fibrosis and 18 cases had no hepatic fibrosis; as just by ultrasound elastography score,43 cases had hepatic fibrosis and 17 cases had no hepatic fibrosis; The sensitivity of ultrasound elastography was 92.9% and the specificity was 77.8%.Strain ratio was（1.61±0.42）at S0 stage,（1.37±0.33）at S1 stage,（0.98±0.23）at S2stage; （0.74±0.27）at S3 stage; （0.59±0.36）at S4 stage. There were significant differences on S0 and other stages（P〈0.05）.Conclusion Using ultrasound elastography to evaluate hepatic fibrosis secondary to hepatitis has comparatively high diagnostic value,which is a new method for clinical diagnosis of hepatic fibrosis,non-invasive and repeatable.