摘要
1例女性8岁患儿（体重38蝇）因急性阑尾炎行阑尾切除术。术前30min肌内注射东莨菪碱0．2mg。麻醉诱导用药为盐酸戊乙奎醚（0．3mg）、咪达唑仑（1．0mg）、芬太尼（80μg）、异丙酚（80mg）和罗库溴铵（25mg），术中以丙泊酚（6～8mg·kg-1·h-1）复合瑞芬太尼（0．2～0．5μg·kg-1·min-1）维持麻醉。手术经过顺利。术后约3h患儿诉视近物模糊，同时有谵妄，双侧瞳孔较正常同龄儿童增大，对光反射存在，眼科会诊考虑抗胆碱类药物性散瞳作用，未予特殊处理。术后约15h谵妄消失，术后约50h视物模糊症状消失。
An 8-year-old girl was scheduled to undergo appendectomy for acute appendicitis. Preoperative conditions were normal. Scopolamine 0.2 mg was intramuscularly injected 30 min preoperatively. Anesthesia was induced by penehyclidine hydroehloride （0.3 mg）, midazolam （ 1.0 mg）, fentanyl （80 μg）, propofol （80 mg） and rocuronium （25 mg）, and propofol （6-8 mg · kg-1 · h-1） and remifentanil （0.2-0.5 μg ·kg-1·min-l） for maintenance. Surgery went smoothly and safely. After three hours, the patient complained of blurred vision, and delirium. Bilateral pupils enlarged as compared with that of normal age, light reflex was normal. Ophthalmological consultation considered it as anticholinergic drug-induced mydriasis, with no special treatment. About 15 h postoperatively delirium disappeared and about 50 h oostooerative blurred vision disanneared.
出处
《药物不良反应杂志》
CSCD
2015年第4期309-310,共2页
Adverse Drug Reactions Journal
关键词
戊乙奎醚
东莨菪碱
谵妄
Penehyclidine
Scopolamine
Delirium
