阿奇霉素序贯治疗支原体肺炎的临床疗效分析

Clinical efficacy of Azithromycin Sequential Therapy in the treatment of mycoplasma pneumonia

目的探讨阿奇霉素序贯疗法用于治疗支原体肺炎的效果,为临床提供参考。方法选取116例肺炎支原体感染的患者,随机分为对照组和治疗组,两组均给予常规治疗,同时对照组使用罗红霉素颗粒进行治疗,治疗组用阿奇霉素序贯疗法进行治疗,观察两组患者主要生理指标变化、临床疗效及不良反应等。结果经治疗后,对照组临床总有效率为72.4%,治疗组为94.8%,两组比较差异有统计学意义(P<0.05);治疗组在体温复常时间、咳嗽消失时间、症状好转时间及住院时间较对照组明显缩短,差异有统计学意义(P<0.05);两组患者均未出现其他严重的不良反应。结论采用阿奇霉素序贯疗法用于治疗支原体肺炎,可显著改善临床症状,缩短住院时间,提高临床疗效,且安全性较好,具有较大的临床借鉴意义。

Objective To discuss the effect of Azithromycin Sequential Therapy in the treatment of mycoplasma pneumonia,and provide reference for clinical practice. Methods 116 patients with mycoplasma pneumonia were selected and randomly divided into treatment group and control group. Both groups were given conventional treatment; the control group was given additionally Roxithromycin Granules,while the treatment group was given Azithromycin Sequential therapy. The main physiological indexes of patients,the clinical efficacy and adverse reactions etc in the two groups were observed. Results The total efficacy rate was 72. 4% in the control group v. s the94. 8% in the treatment group（ P 〈0. 05）; The treatment group was superior to the control group in time to regain normal temperature,time to cough disappearance,time to symptom improvement and hospitalization time,with significant difference（ P〈 0. 05）; No serious adverse reactions were not found in the two groups of patients. Conclusion Use of Azithromycin Sequential Therapy for the treatment of mycoplasma pneumonia can significantly improve the clinical symptoms,shorten the hospitalization time,and improve the clinical efficacy with better safety,thus has great clinical significance.