玄参药材质量控制研究进展

Quality Control of Scrophulariae Radix

综述玄参质量控制研究新进展。通过调研近年文献,表明玄参主要有效成分为环烯醚萜苷类。全国大部分地区都有栽培,但是玄参质量标准未趋于完善和规范,量化控制水平也存在不足,所以玄参质量有所差异。当前控制中药质量的发展趋势是质量控制多元化,并建立多模式多色谱系统及其联用技术的质量控质方法。玄参的质量控制模式目前主要以单指标,多指标质控,指纹图谱为主,高效液相色谱(HPLC),高效毛细管电泳(HPCE),近红外光谱(NIRS),衰减全反射光谱(ATR)等技术为系统控制和评价玄参的质量提供方法和新技术上的探索。以上对玄参化学成分和质量控制等内容提供借鉴。为玄参资源的进一步开发与利用提供依据。

The advance in studies on the quality control of Scrophulariae Radix was summarized. Literatures in recent years were studied to define the main active ingredient in S. ningpoensis is iridoid glycosides. Although Scrophulariae Radix has grown in most areas of China, there is no improved quality standards and norms and sufficient quantitative control, which resulted in differences in quality control. The current development trend for controlling traditional Chinese medicine quality is to diversify the quality control mode and establish the multi- mode multi-chromatography system and its coupling technique quality control method. Currently, the quality control mode for Scrophulariae Radix is dominated by single index, multi-index quality control and fingerprint; HPLC, high performance capillary electrophoresis （HPCE）, near-infrared spectroscopy （NIRS）, attenuated total reflectance （ATR） and other techniques lay a foundation for exploring methods and new techniques for systematic control and evaluation for Scrophulariae Radix. The above content provides the reference for chemical components and quality control of Scrophulariae Radix and the basis for further development and utilization of Scrophulariae Radix resources.