安徽省成人高尿酸血症患病率及相关危险因素分析

Prevalence and the risk factors of hyperuricemia in adult population in Anhui province

目的探讨安徽省成人高尿酸血症患病率及相关危险因素。方法应用2010年安徽省成人慢性肾脏病调查数据,分析安徽省成人高尿酸血症患病情况及相关危险因素。结果研究调查了安徽省18岁以上常驻居民3 800例,其中资料完整者3 374例。检出高尿酸血症患者260例,其中男性133例,女性127例,粗患病率为7.70%。经安徽省常驻人口年龄、性别校正后,高尿酸血症患病率分别为7.04%、7.88%。Logistic回归分析发现民族、文化程度、肥胖、饮酒、高血压、高脂血症及慢性肾脏病可能是高尿酸血症的独立危险因素。结论高尿酸血症的危险因素与国内外研究一致,积极控制体质量和血脂、减少饮酒有助于预防高尿酸血症。

Objective To investigate the prevalence and the risk factors of hyperuricemia among the adult population in Anhui province. Methods The data of Chronic Kidney Disease Survey for Adults in Anhui Province in 2010 were used in this study for analyzing the prevalence and risk factors of hyperuricemia. Results The survey data were from 3 800 individuals, including 3 374 with complete data. And 260 were diagnosed as hyperuricemia （male 133; female 127）, with the crude prevalence of hyperuricemia in Anhui province being 7.70%. After adjusting the age and gender of residents, the prevalences of hyperuricemia were 7.04% and 7. 88%, respectively, in Auhui province. Logistic regression analysis showed that ethnicity, education background, body mass index, alcohol consumption, hypertension, hyperlipidemia and chronic kidney disease might be independent risk factors for hyperuricemia. Conclusion The risk factors of hyperuricemia in the present study are consistent with previous domestic and international findings. Active control of body weight, blood lipid, and alcohol intake can help to prevent hyperuricemia.