脑卒中与阻塞性睡眠呼吸暂停低通气综合征之间关系的研究新进展

New Progress in the Relationship Between Stroke and Obstructive Sleep Apnea Hypopnea Syndrome

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)所造成的慢性缺血缺氧性损伤危害机体各个系统,如可致高血压、高血糖、高粘血症等,后者是脑血管病的常见危险因素,而仅仅降压、降糖等是不足的。通过对大量脑卒中合并OSAHS的患者进行呼吸机辅助呼吸治疗后发现,在改善其睡眠质量的同时,其脑卒中的恢复情况有改善,再患率也下降。本文着重探讨OSAHS致高粘血症从而进展为脑卒中的发病机制,观察经鼻持续气道内正压通气(n CPAP)治疗后神经功能改善情况,以及提出未来研究方向。

After giving the treatment of ventilator-assisted breathing for the stroke patients with OSAHS,we found that the recovery of its stroke significantly improved while the prevalence rate decreased largely.The folowing focuses on how the OSAHS caused high blood viscosity thus progressed to the pathogenesis of stroke,observing the neurological improvement after the treatment of nasal continuous positive airway pressure （nCPAP） and proposing future research directions.