厄贝沙坦联合氨氯地平治疗早期糖尿病肾病合并高血压临床疗效观察

Clinical Observation on Irbesartan Combined With Amlodipine in the Treatment of Early Diabetic Nephropathy With Hypertension

目的研究厄贝沙坦联合氨氯地平治疗早期糖尿病肾病合并高血压的临床疗效。方法将80例糖尿病肾病合并高血压患者随机分为研究组和对照组A、对照组B。研究组以厄贝沙坦联合氨氯地平治疗,对照组A仅给予厄贝沙坦,对照组B仅给予氨氯地平。对比各自临床表现。结果研究组不良反应发生率15.4%,对照组A为37.0%,对照组B为33.3%,组间比较有差异。结论联合用药疗效良好,并对肾功能有一定保护作用。

Objective Study on the clinical efficacy of irbesartan combined with amlodipine in the treatment of early diabetic nephropathy with hypertension. Methods80 patients with diabetic nephropathy combined with hypertension were randomly divided into study group and control group A,control group B. The study group with irbesartan combined with amlodipine treatment,the control group A was given irbesartan,B of the control group was given amlodipine.ResultsThe incidence of adverse reactions in the study group was 15.4%,the control group A was 37%, the control group B was 33.3%,there were significant differences between the groups. Conclusion The efficacy of combination therapy is more obvious,and it has some protective effect on renal function.