长期口服阿司匹林致老年人上消化道出血及Hp感染30例分析

Analysis of 30 Cases of Elderly Patients With Upper Digestive Tract Hemorrhage and Hp Infection Caused by Long-term Oral Aspirin

目的：探讨分析长期口服阿司匹林肠溶片老年患者大便隐血及幽门螺杆菌抗体检验的结果，正确指导患者科学合理用药，以预防和减少上消化道出血的发生。方法采集30例长期口服阿司匹林肠溶片患者的大便及血样进行检测，同时进行停药后采集大便及血样进行检测，结合胃镜检查诊断溃疡病例，并对检测结果进行分析。结果30例长期口服阿司匹林肠溶片患者的大便隐血试验均有不同程度的阳性显示，胃镜检查，胃黏膜有不同程度的损伤，幽门螺杆菌抗体检查12例Hp感染。适当停药后大便隐血试验全部为阴性，随访3～6个月无再出血。结论长期口服阿司匹林肠溶片患者应该定期进行常规化验检查，密切注意有无出血倾向，根据个体差异掌握合适剂量，同时加用胃黏膜保护剂，以预防和减少上消化道出血的发生。

Objective Discuss long-term oral enteric aspirin tablets elderly patients defecate occult blood and helicobacter pylori antibody test results, patients with right guidance scientific and rational drug use, in order to prevent and reduce the occurrence of upper gastrointestinal bleeding. Methods 30 patients with long-term oral enteric aspirin tablets stool and blood samples for testing were chosen, after discontinuation of simultaneous collection stool and blood samples for testing,in combination with gastroscopy diagnosis cases of ulcer, and the test results were analyzed. Results 30 cases of patients with long-term oral enteric aspirin tablets defecate occult blood test all have varying degrees of positive display, gastroscopy had different degree of gastric mucosal injury, helicobacter pylori antibody examination 12 cases of Hp infection. After discontinuation of appropriate defecate occult blood test are all negative, no further hemorrhage were followed up for 3~6 months. Conclusion Should be on regulars basis for long-term oral aspirin were examined by routine tests, pay close attention to any bleeding tendency, according to the individual differences to master appropriate dose, at the same time combined with gastric mucosa protectant, in order to prevent and reduce the occurrence of upper gastrointestinal bleeding.