PICCO容量性指标在感染性休克液体复苏中的应用

Clinical Application of PICCO Capacity Index Used in Fluid Resuscitation of Septic Shock

目的：探讨PICCO容量性指标在感染性休克液体复苏中的应用效果。方法选取我院2011年1月～2014年12月收治感染性休克患者110例，随机分为对照组（55例）和观察组（55例），分别采用常规液体复苏和PICCO容量性指标监测下行液体复苏治疗；比较两组患者死亡率、呼吸机使用时间、重症监护时间、中心静脉氧饱和度及乳酸水平等。结果观察组患者死亡率低于对照组，差异有统计学意义（P＜0.05）；观察组患者呼吸机使用时间和重症监护时间均短于对照组，差异有统计学意义（P＜0.05）；而观察组患者中心静脉氧饱和度和乳酸水平均优于对照组，差异有统计学意义（P＜0.05）。结论PICCO容量性指标用于感染性休克液体复苏可有效降低死亡率，促进病情缓解，并有助于提高补液准确度。

Objective To investigate the clinical application effects of PICCO capacity index used in lfuid resuscitation of septic shock. Methods 110 patients with septic shock in recent years in our hospital were chosen and randomly divided into two groups including control group （55 patients） with conventional fluid resuscitation and observation group （55 patients） with PICCO capacity index used in lfuid resuscitation, and the mortality, duration of ventilator use and critical care and levels of central venous oxygen saturation and lactate of both groups were compared. Results The mortality of observation group were signiifcantly better than control group （P〈0.05）. The duration of ventilator use and critical care of observation group were signiifcantly better than control group （P〈0.05）. The levels of central venous oxygen saturation and lactate of observation group were significantly better than control group （P〈0.05）. Conclusion Compared with conventional lfuid resuscitation, PICCO capacity index used in lfuid resuscitation of septic shock can efifciently decrease the mortality, promote disease remission and be helpful to improve the accuracy of lfuid infusion.