高同型半胱氨酸血症与冠心病心力衰竭关联分析

Association Between High Homocysteine and Coronary Heart Disease With Heart Failure

目的：观察高同型半胱氨酸血症（HHCY）与冠心病心力衰竭的相关性。方法选择我院2013年2月～2015年2月收治的53例冠心病心力衰竭患者作为观察组，选择冠心病但无心力衰竭作为对照组1；选择无冠心病及慢性心衰患者作为对照组2。对比观察三组患者HCY水平及不同心功能分级下患者的HCY水平情况。结果观察组、对照组1患者发生HHCY比例高于对照组2患者（P＜0.05）。观察组与对照组1患者HCY浓度与对照组2比较，差异具有统计学意义（P＜0.05）。NYHAIII患者与NYHAIV患者HCY浓度高于NYHAII患者（P＜0.05）。结论 HHCY与冠心病心力衰竭呈正相关关系，是心衰及冠心病的危险因素。

Objective Observation of hyperhomocysteinemia （HHCY） and coronary heart relevance. Methods 53 cases of patients with coronary heart disease were chosen as the observation group in our hospital from February 2013 to February 2015, select coronary heart disease but without heart failure as the control group 1, choose without coronary heart disease and chronic heart failure patients as a control group 2. Comparative study of three groups of patients HCY levels and cardiac function under different circumstances HCY levels in patients. Results Observation group and control group 1 was significantly higher in patients HHCY 2 patients （P〈0.05）. Observation group and control group 1 patients HCY concentration and control group 2 compared the results with a signiifcant difference （P〈0.05）. NYHAIII patients with HCY concentrations were significantly higher than NYHAII and NYHAIV patients （P〈0.05）. Conclusion HHCY and positively correlated with coronary heart disease, heart failure and is a risk factor for coronary heart disease.