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Optimal Design Strategies of Femur Tumor Hyperthermia Based on Finite Element Analysis of Temperature Field

Optimal Design Strategies of Femur Tumor Hyperthermia Based on Finite Element Analysis of Temperature Field
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摘要 A 3D femoral model was built to obtain the three-dimensional temperature distribution of femur and its surrounding tissues and provide references for clinical applications. According to the relationship between gray-value and material properties,the model was assigned with various materials to make sure that it is more similar to the real femur in geometry and physical properties. 3D temperature distribution is obtained by using finite element analysis software ANSYS 11. 0 on the basis of heat conduction theory,Laplace equation,Pennes bio-heat transfer equation,thermo physical parameters of bone tissues,the boundary condition,and initial conditions. Taken the asymmetry of the 3D distribution of temperature into account,it is necessary to adopt the heating method with multiple heat sources. This method can ensure that the temperature fields match well with the tumor tissues and kill the tumor cells efficiently under the condition of protecting the normal tissues from damage. The analysis results supply important guidance for determining the needle position and the needle number and controlling the intensity of heating. A 3D femoral model was built to obtain the three-dimensional temperature distribution of femur and its surrounding tissues and provide references for clinical applications. According to the relationship between gray-value and material properties,the model was assigned with various materials to make sure that it is more similar to the real femur in geometry and physical properties. 3D temperature distribution is obtained by using finite element analysis software ANSYS 11. 0 on the basis of heat conduction theory,Laplace equation,Pennes bio-heat transfer equation,thermo physical parameters of bone tissues,the boundary condition,and initial conditions. Taken the asymmetry of the 3D distribution of temperature into account,it is necessary to adopt the heating method with multiple heat sources. This method can ensure that the temperature fields match well with the tumor tissues and kill the tumor cells efficiently under the condition of protecting the normal tissues from damage. The analysis results supply important guidance for determining the needle position and the needle number and controlling the intensity of heating.
出处 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2015年第4期121-128,共8页 哈尔滨工业大学学报(英文版)
基金 Sponsored by the National Natural Science Foundation of China(Grant No.61272387) the Program for New Century Excellent Talents in University(Grant No.NCET-13-0756) the Distinguished Young Scientists Funds of Heilongjiang Province(Grant No.JC201302)
关键词 FEMUR tumor hyperthermia 3D temperature fields finite element analysis femur tumor hyperthermia 3D temperature fields finite element analysis
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