支架植入手术对颈动脉狭窄合并认知功能障碍患者术后脑血流动力学变化的影响

Preliminary study of cerebral hemodynamics changes in patients with carotid artery stenosis and cognitive dysfunction treated by stent implantation

目的探讨支架植入手术对颈动脉狭窄合并认知功能障碍患者术后脑血流动力学变化的影响。方法选取我院2010-01—2014-12收治的30例颈动脉狭窄合并认知功能障碍患者,所有患者均行支架植入手术,手术前后分别采用简易精神评估量表(MMSE)和蒙特利尔认知估量表(MoCA)评价认知功能,观察治疗效果。结果手术前MMSE和MoCA评分显著低于术后3个月,差异有统计学意义(P<0.05);术后rCBF与rTTP低于术前,其他高于术前,差异有统计学意义(P<0.05);患者术后血液流变参数均显著低于对照组,差异有统计学意义(P<0.05)。结论支架植入手术有利于改善患者脑血流动力学变化情况,也提高了患者的认知功能,有利于患者早日康复。

Objective To explore cerebral hemodynamics changes in patients with carotid artery stenosis and cognitive dys‐function treated by stent implantation .Methods 30 cases with carotid artery stenosis and cognitive impairment from January 2010 to December 2014 in our hospital were selected ,all patients underwent stent implantation .We performed the mini mental assessment scale （MMSE） and the Montreal cognitive assessment scale （MoCA） to evaluate the cognitive function before and after surgery and observed therapeutic effects .Results MMSE scores and MoCA scores 3 months after surgery were signifi‐cantly lower than that before surgery with statistical difference （P〈0 .05）;rCBF and rTTP after operation were lower than that before operation ,others were higher （P〈0 .05） .Compared with before operation ,hemorheological parameters after oper‐ation showed statistical difference with higher parameters （P〈0 .05） .Conclusion Stent implantation can not only improve cer‐ebral hemodynamics changes ,but also improve the cognitive function ,which is conducive to recovery .