卒中样表现脑胶质瘤的影像学研究及与预后的相关性分析

The imaging study and the related prognostic analysis of glioma with stroke-like performance

目的分析卒中样表现脑胶质瘤的影像学参数及与预后的相关性。方法选取2011-03—2013-03收治的卒中样表现胶质瘤患者进行动态CT扫描,对比CT扫描参数和胶质瘤的MVD之间的相关性及MVD与患者预后相关性。结果病理分级Ⅰ~Ⅱ级与Ⅲ级的MVD组间比较差异有统计学意义（P〈0.05）;Ⅰ级和Ⅳ的MVD数据对比差异有统计学意义（P〈0.05）。动态CT扫描参数对比,Ⅰ级和Ⅱ级间的TBRp、TBRL和Sa参数对比差异无统计学意义（P〉0.05）;而Ⅰ~Ⅱ级和Ⅲ~Ⅳ组间对比差异有统计学意义（P〈0.05）。TBRp、TBRL和Sa与胶质瘤的MVD呈正相关。动态CT扫描得到的TBRp、TBRL和Sa参数越大,患者的MVD值越高。术后发生复发患者MVD值明显要比没有出现复发的患者高,2组对比差异有统计学意义（P〈0.05）;而存活率对比方面,〈3a存活率患者的MVD值明显比≥3a的患者高,差异有统计学意义（P〈0.05）。结论通过动态CT扫描等影像学检查参数预测胶质瘤患者MVD值,可预测患者术后的预后质量。

Objective To observe and analyze the imaging parameters and its relationship with prognosis of glioma with stroke‐like performance. Methods We recruited glioma cases with stroke‐like performance from March 2011 to March 2013 to carry out dynamic CT scan ,then analyzed the correlation between CT scan parameters and MVD as well as the relationship be‐tween MVD and prognosis. Results In MVD outcome ,the pathological grade I and II compared with grade III ,the result re‐vealed relatively significant difference （P〈 0.05）;and grade I and IV of MVD data also reached statistical difference （P〈0.05）. In dynamic CT scan parameters ,as to TBRp ,TBRL and Sa parameter ,the difference was not statistically significant between grade I and grade II （P＆gt;0.05）;but the result showed significant difference when compared grade I ~ II with grade III ~ IV （P〈0.05） ,and there was a positive correlation between TBRp ,TBRL ,Sa glioma and MVD ,namely ,the bigger pa‐rameters the TBRp ,TBRL and Sa got ,the higher values the MVD reached. MVD values in recurrent patients were significant‐ly higher than that in non‐recurrent patients ;in addition ,MVD values in the patients with 〈3‐year survival time were signifi‐cantly higher than that in those with ≥ 3‐year survival time. Conclusion We can predict the prognosis of glioma patients through MVD values assessed by dynamic CT scan parameters.