军智Ⅰ号饮料包对长时连续脑力作业神经行为功能的改善作用研究

Effect of Junzhi beverage Ⅰon neurobehavioral functions in subjects exposed to longterm sustained work

目的评估本中心研制的军智Ⅰ号饮料包对长时连续脑力作业神经行为功能的改善作用。方法选取某军校40名学员为受试者,随机分为对照组（n=20）和干预组（n=20）,受试者于测试日进行连续10 h（8∶00-18∶00）高强度脑力作业,干预组于12∶50服用军智Ⅰ号,所有受试者于17∶00按照WHO规定的测试方法、顺序及分组进行WHO神经行为核心测试组合（neurobehavioral core test battery,WHO-NCTB）测试及注意广度测试。结果 WHO-NCBT测试发现,长时连续脑力作业后干预组心境状态较对照组稳定,表现为不良情绪得分较低,而正性情绪得分较高;干预组较对照组简单反应时测试平均反应时间缩短且错误反应次数减少,数字倒序、视觉保留及数字译码、习惯用手提转捷度及目标追踪正确数则明显增加（P〈0.05）。此外,干预组在长时连续脑力作业后注意广度测试正确数也显著高于对照组（P〈0.05）。结论本中心研制的军智Ⅰ号饮料包可显著改善长时连续脑力作业后期神经行为功能,具有延缓脑力疲劳产生、保护和增强认知功能的作用。

Objective To determine the ameliorative effects of Junzhi beverage I on neurobehavioral functions in subjects exposed to long-term sustained work. Methods Forty male students of a military institution were randomized into control group （ n = 20） and the intervention group （ n = 20）. All the subjects were exposed to 10-hours＇ high intensity mental work continuously （8：00 -18： 00）. At 12： 50, the intervention group drunk a bottle of water with Junzhi beverage I, but the control group drunk water of the same volume only. At 17： 00, neurobehavioral functions of all the subjects were tested by neurobehavioral core test battery （WHO-NCTB） and attention span test （AST）. Results According to the results of WHO-NCBT, after 10-hours＇ continuous mental work, the profile of mood state in the intervention group was more stable than in the control group with lower scores in negative mood and higher scores in positive mood. Meanwhile, some of the neurobehavioral indexes were also found to be significantly improved, including shortened mean time of simple reaction and decreased error reaction rate, enhanced digit span backward, higher scores in Beton test , digit symbol test, Santa Aria practice hand and correct dot number （P 〈 0.05）. In addition, higher scores were obtained in the intervention group in AST（P 〈 0.05）. Conclusion Junzhi beverage I can significantly improve the neurobehavioral function under sustained mental work conditions, which suggests that the beverage has the potential to postpone mental fatigue protect and enhance cognitive function.