干预前后医院急诊抗菌药物应用对比分析

Comparative Analysis of Antibiotics Application in Emergency Department of A Hospital

目的了解医院抗菌药物的临床应用现状及存在的问题,调查急诊科贯彻《抗菌药物临床应用管理办法》情况并评价其用药合理性。方法随机抽取2012年1月至3月(干预前)和2013年1至3月(干预后)急诊科处方各1 500张,对抗菌药物使用情况及合理性进行统计分析。结果干预前抗菌药物处方525张,使用比例35.00%,抗菌药物金额占所有处方的38.74%;2013年1月至3月干预后抗菌药物处方423张,使用比例28.20%,抗菌药物金额占所有处方的32.86%。2013年非限制级抗菌药物的使用率较2012年显著提高。急诊科抗菌药物不合理使用的情况主要包括适应证不适宜、用法用量不合理、联合用药不合理。结论医院急诊处方抗菌药物的应用情况基本合理,但仍需进一步加强抗菌药物合理应用,以提高医院临床用药的安全性、有效性和经济性。

Objective To analyze the present status of antibiotics application and to investigate the implementation of ＆quot;Control Measures of Antibiotics Clinical Treatment＆quot; in the emergency department of the hospital and the rational use of antibiotic combination in clinic. Methods Totally 1 500 pieces of emergency prescriptions from January to March in 2012 and 2013 were randomly selected for a retrospective investigation to evaluate the rationality of antibiotics application. Results There were 525 pieces about antibacterial agents in 2012,usage rate was 35. 00%,and the cost rate was 38. 74%;there were 423 pieces about antibacterial agents in 2013,usage rate was 28. 20% and the cost rate was 32. 86%. The usage rate of non-limited antibacterial agents in 2013 was significantly higher than in 2012. The irrational application of antibiotics included inappropriate indications,unreasonable dosage and irrational combination. Conclusion The antibiotic usage of the hospital is basically reasonable,but it still need to be improved with control measures in order to make antibiotics application safe,effective and economic.