复苏后综合征的中西医研究现状

Progress of treating post resuscitation syndrome with Chinese and western medicine

复苏后多器官功能障碍综合征(MODS),即复苏后综合征(PRS)是危重病患者死亡的主要原因之一,表现为恢复自主循环后出现的低血容量性休克、心源性休克和与全身炎性反应综合征(SIRS)相关的血管扩张性休克。多种致病因素均可导致PRS的发生,由于其发病的明确诱因,切断发病的始动因素最为关键。目前PRS的治疗措施虽然很多,但缺乏实质性的进展,没有有效的治疗药物,预防就是最好的治疗,其中改善复苏后早期血流动力学不稳定及有效脑复苏是最重要的。同时中医药治疗复苏综合征是趋势与新领域,积极拓展相关中医药治疗将为其治疗提供进一步思路与方向。

Multiple organ dysfunction syndrome （MODS）, namely post resuscitation syndrome （PRS）, is one of the leading causes of death among critical ill patients. The manifestations of RPS include hypovolemic shock, cardiogenic shock and vasodilatory shockassociated with systemic inflammatory response syndrome （SIRS） after restoration of spontaneous circulation （ROSC）. A variety of pathogenic factors can lead to PRS. Because of the specific causes, the most critical step of PRS treatment is cutting off the key factors in the pathogenesis. Although there are many treatments for PRS at present, it is still lack of substantial progress, and with no effective drug forthe treatment of PRS. Prevention is the best treatment of PRS, in which to improve the early hemodynamic instability after the recovery and resuscitate cerebraeffectively is the most important. Simultaneously, treating PRS with traditional Chinese medicine （TCM） is a new tendency, and it will provide a new train of thought and direction for the treatment of this disease by expandingTCM treatmentsactively.