宁波地区早期糖尿病肾病患者中医体质类型分布研究

Research on distribution of TCM constitution types of patients with early diabetic nephropathy in Ningbo

目的:探讨宁波地区早期糖尿病肾病(DN)中医体质类型特点,为早期DN的防治提供依据。方法:研究采用王琦教授中医体质九分法对宁波地区早期DN患者287例与健康对照人群297名进行中医体质调查,并运用构成比、Logistic回归分析法比较2组中医体质特征的差异。结果:研究发现血瘀质(38.04%)、气虚质(26.90%)、阴虚质(16.03%)为宁波地区早期DN的高频体质。通过Logistic回归分析发现气虚质、阴虚质、血瘀质、平和质为早期DN的危险因素,对早期DN的影响,平和质>血瘀质>气虚质>阴虚质。结论:血瘀质、气虚质、阴虚质、平和质为宁波地区早期DN的高发体质。血瘀质个体早期DN发病倾向最大。

Objective： To investigate the characteristic of traditional Chinese medicine （TCM） constitution types of patients with early diabetic nephropathy （DN） in Ningbo, and provide basis for the treatment and prevention of patients with early DN. Methods： The TCM constitution of 287 patients with early DN and 297 healthy people was surveyed by using TCM constitution rule of nines, and the difference in constitution characteristics between the two groups was compared by using constituent ration and Logistic regression analysis methods. Results： The high frequency constitutions of early DN in Ningbo were stagnant blood constitution （38.04%）, qi deficiency constitution （26.90%） and yin deficiency constitution （16.03%）. The results of logistic regression analysis showed that qi deficiency constitution, yin deficiency constitution, stagnant blood constitutionand mild constitution were the risk factors of early DN, and the influence of the above factors was as follows： mild constitution〉stagnant blood constitution〉qi deficiency constitution〉yin deficiency constitution. Conclusion： The high incidence constitutions of early DN are qi deficiency constitution, yin deficiency constitution, stagnant blood constitution and mild constitution in Ningbo, and the morbidity of early DN is the highest in stagnant blood constitution.