支气管肺泡细胞癌误诊分析

Misdiagnosis analysis of bronchioloalveolar carcinoma

目的回顾性分析支气管肺泡细胞癌（bronchioloalveolar carcinoma，BAC）临床特点，提高早期BAC的确诊率，减少误诊。方法对2013年一2014年间在我院确诊的BAC病例5例的临床资料进行回顾性分析。结果5例患者中男4例，女1例，年龄在50—73岁之间，在社区医院均曾误诊为肺炎，所有患者均在我院经支气管镜肺活检后确诊为BAC。结论BAC是一种较为特殊的肺癌，临床上症状无特异性，极易误诊为普通肺炎。由于BAC预后差，误诊后果严重，对初诊为普通肺炎的患者经常规抗感染治疗后临床症状及影像学表现改善不明显时，应及时进行各项检查、明确诊断，以便有效改善患者预后。

Objective To elevate the clinical diagnosis of BAC （bronchioloalveolar carcinoma） so as to reduce misdiagnosis by using retrospective analyses. Methods Retrospective analyses were used to study the five BAC patients, who were diagnosed in our hospital from 2013 to 2014. Results 4 of 5 male, and i female, age between 50 and 73, were diagnosed as pneumonia. All of them were made a definite diagnosis as BAC after performing transbronchial lung biopsy. Conclusion BAC is an exceptional lung adenocarcinoma and there is no specific clinic symptom. BAC was easily misdiagnosed as common lung pneumonia. There will be serious consequences after misdiagnosis of BAC due to its poor prognosis. Those patients who were misdiagnosed as common lung disease, but there was no obvious improvement after accepting long anti-infective therapy and there was negatively detection of pathogenic bacteria in them, are needed to perform all other clinical examination to clarify a diagnosis, and to further improve the prognosis of the patients.