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高危急性髓系白血病的诊疗进展 被引量:3

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摘要 急性髓系白血病(AML)是一种异质性很强的疾病,其预后与生物学分型密切相关。根据细胞遗传学及分子生物学检查将AML分为低危、中危及高危。高危AML的生物学特征是细胞遗传学异常及分子基因的异常,临床表现为对诱导化疗反应差,生存期短,易复发,并对目前常规化疗方案耐药。异基因造血干细胞移植是目前根治高危AML的最好方法,试验性治疗可采用细胞毒性药物、免疫调节药物、靶向药物及化疗増敏药物。
出处 《山东医药》 CAS 北大核心 2015年第34期94-96,共3页 Shandong Medical Journal
基金 国家自然科学基金资助项目(31301161 81270603)
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