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shRNA介导的基因沉默表达载体构建方法及应用 被引量:1

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摘要 shRNA即短发夹RNA,是设计为能够形成发夹结构的非编码小RNA分子,可通过RNA干扰来抑制基因的表达,其干扰原理是指在进化过程中高度保守的、由双链RNA诱发的、同源mRNA高效特异性降解的现象。本文综述了shRNA表达载体的构建方法,并对其在生物领域研究中的应用前景进行了探讨。
出处 《上海畜牧兽医通讯》 2015年第5期18-19,22,共3页 Shanghai Journal of Animal Husbandry and Veterinary Medicine
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参考文献13

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