100例高血压病患者短程心率变异性分析

Analysis of Short-term Heart Rate Variability in 100 Cases with Hypertension Disease

目的:评价自主神经活动在高血压病中的调节作用。方法:观测100例高血压病(Ⅰ组)和54例正常人(Ⅱ组)及高血压病伴心电图改变(ⅠA组)和不伴心电图改变(ⅠB组)心率变异性(以下称HRV)时域参数SDNN、rMSSD、PNN50、Bottom4项指标。结果:Ⅰ组与Ⅱ组差异有显著性(P<0.05);ⅠA组与ⅠB组组差异无显著性(P>0.05)。结论:在高血压病中,交感神经张力增高,副交感神经活动减弱及损伤可能是HRV降低的重要因素。

Objective:To evaluate the modulation role of autonomic nerve activity in hypertension disease.Methods:Four time-dependent indexes of heart rate variability(HRV)SDNN,rMSSD,PNN50 and Bottom were observed in 100 cases with hypertension disease (group I ),54 normal citizens (group Ⅱ )and hypertension disease with changes of electrocardigram (group IA) and without any change of electrocardiogram (group I B). Results: There was significant difference between group I and group Ⅱ ( P < 0.05) . There was no significant difference between group I A and group I B( P > 0.05) .Conclusion:Sympathetic nerve tension heightening , Parasympathetic nerve activity bating and injuring may be the important considerations of the decrease of HRV in hypertension disease.