3D SPACE STIR结合DTI显示腰骶神经根病变的研究

The study of lumbosacral radiculopathy combined with 3D SPACE STIR and DTI

目的 探讨结合DTI的短回波反转恢复各向同性变换角度RF激发3DT2TSE序列（SPACE：Sampling Perfection with Application optimized Contrasts using different flip angle evolutions）在腰骶丛病变成像中的应用价值。方法10例健康志愿者和32例腰骶丛神经病变患者行常规扫描序列、3DSPACE STIR序列和DTI序列扫描。结果 10名健康自愿者,L1~S1腰骶神经根3DSPCACE STIR序列均得到清晰显示。32例腰骶丛神经病变中,神经根受推压移位27例,受侵犯5例。椎间盘突出所致神经根受损的FA值降低（P〈0.05）,而ADC值升高（P〈0.05）。结论 3DSPACE STIR序列具有较好的组织对比,图像可被作为测量DTI数据的FA值及ADC值的高分辨率蒙片,两者结合可以很好评估腰骶神经丛的神经压迫位置和神经受侵犯的范围和程度。

Objective To evaluate isotropic 3D T2 turbo-spin-echo （TSE） sequence with short-term inversion recovery （STIR） and variable flip angle RF excitations SPACE （Sampling Perfection with Application optimized Contrasts using different flip angle Evolutions） with DTI in high-resolution imaging of lumbosacral plexus. Methods 10 healthy volun- teers and 32 patients with lumbosacral plexus neuropathy patients were studied with conventional, 3D STIR SPACE and DTI sequence. Results In 10 healthy volunteers, L1 ~S1 of lumbosacral nerve root were clearly display by 3D SPCACE STIR sequence. In 32 cases of lumbosacral plexus neuropathy, nerve root was pushing the shift in 27 cases, 5 cases with invasion. Intervertebral disc herniation caused by nerve root damage FA values than normal people （ P 〈0.05） decreased, while the ADC value increased than in the normal people （ P〈0.05）. Conclusion 3D SPACE STIR sequence has good tissue contrast, and the image can be used as high resolution mask measurement of DTI data of FA value and ADC value. A combination of the two can be a very good evaluation of lumbosacral plexus nerve compression position and violations of the scope and extent of nerve.