摘要
目的:探讨中等剂量托吡酯(商品名:妥泰)200mg对特发性全面性强直阵挛(GTCS)发作的疗效。方法:64例GTCS患者分成三组,妥泰单药治疗21例,妥泰联合丙戊酸钠治疗22例,另外21例采用丙戊酸钠治疗作对照。结果:妥泰单药组及联用药组治疗GTCS有效例数明显高于单用丙戊酸钠组,差异显著(P<0.05);同时单用妥泰组与联用丙戊酸钠组疗效相近(P>0.05)。结论:妥泰治疗GTCS疗效优于丙戊酸钠,且妥泰单一用药与联用丙戊酸钠治疗疗效相近。
Objective:To study the curative effect of middle dose of topiramate (200mg) on general tonic clonic seizure. (GTCS) Methods: 64cases of GTCS were divided into three groups. Group A: 22 cases of GTCS were treated with topiramate. Group B: 22 cases of GTCS were treated with topiramate plus sodium valproate.The other 21 cases group C received treatemnt with sodium valproate. Results: The effective rate in group A and B was higher than that in group C (P < 0.05 ) , and group A was similar to group B in the curative effect. The curative effect of topiramate for GTCS is better than sodium valproate. The curative effect of topiramate for GTCS. is similar to topiramate plus sodium valproate
出处
《医学理论与实践》
2002年第8期899-900,共2页
The Journal of Medical Theory and Practice
