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依托咪酯与异丙酚对老年患者腹腔镜手术血流动力学及术中知晓的影响 被引量:7

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摘要 在脑功能状态指数(CSI)的监测下将依托咪酯与异丙酚分别用于老年患者腹腔镜手术的麻醉,观察其围手术期血流动力学变化及术中知晓的情况。80例老年腹腔镜手术患者随机分为依托咪酯组(A组)和异丙酚组(B组)。分别于麻醉诱导前(t0)、气管插管时(t1)、气腹时(t2)、手术进展30 min时(t3)和手术结束时(t4)记录各组心率(HR)、平均动脉压(MAP)及CSI值;术后判断术中知晓情况。两组t1时HR、MAP差异有统计学意义(P<0.05),其余4个时段差异无统计学意义(P>0.05)。B组各时段HR、MAP波动较大,差异有统计学意义(P<0.05);A组各时段HR、MAP较为平稳,差异无统计学意义(P>0.05)。CSI值各组间比较差异均无统计学意义(P>0.05)。两组的苏醒时间、拔管时间差异无统计学意义(P>0.05),A组在怀疑有知晓、恶心呕吐、心动过缓发生等情况均低于B组,但无统计学意义(P>0.05)。依托咪酯在保持稳定生命体征的同时,同异丙酚一样能保证适宜的麻醉深度,且能够降低麻醉手术对老年患者血流动力学的影响,保障老年患者的生命安全。
出处 《中国现代普通外科进展》 CAS 2015年第8期649-651,共3页 Chinese Journal of Current Advances in General Surgery
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