东北地区军人肠易激综合征患者心理应激因素以及焦虑、抑郁情况调查

Psychological Stress Factor,Anxiety and Depression in Irritable Bowel Syndrome Patients among Soldiers in Northeast Area

背景:肠易激综合征(IBS)的发病机制尚不清楚,社会心理因素被认为是其发病的重要原因,尤其是焦虑、抑郁与IBS的关系日益被关注。目的:调查东北地区军人IBS患者的心理应激因素以及焦虑、抑郁情况。方法:采用多级、分层、整群抽样方法选取东北地区11 400名军人,采用问卷调查进行IBS的调查,行Zung氏焦虑自评量表(SAS)和抑郁自评量表(SDS),分析焦虑、抑郁与应激因素的关系。结果:IBS的患病率为15.9%,IBS组焦虑、抑郁患病率分别为22.9%和26.6%,显著高于非IBS组的9.6%和12.4%(P<0.05)。IBS组SAS、SDS评分分别为50.86±7.27和53.47±7.86,明显高于非IBS组的36.54±6.97和38.25±9.83(P<0.05)。IBS患者的SAS评分和SDS评分均与感觉寂寞、情绪沮丧、训练强度大、工作压力大、与同事关系差、处置过突发事件或参加过军事演习等因素呈正相关(P<0.05)。结论:军人这一特殊群体的IBS发生与应激和心理因素密切相关。

Background： The pathogenesis of irritable bowel syndrome （IBS） is not fully known, social psychological factor is the important factor of IBS, especially the relationship with anxiety and depression. Aims： To investigate psychological stress factor, anxiety and depression in IBS patients among soldiers in northeast area. Methods： A total of 11 400 soldiers in northeast area were enrolled by multistage, stratified, cluster random sampling method asking to fulfill a questionnaire on IBS. Zung self-rating anxiety scale （SAS） and Zung self-rating depression scale （SDS） were assessed, and the relationship with anxiety, depression and stress was analyzed. Results ： The incidence of IBS was 15.9%. Prevalences of anxiety and depression in IBS group were significantly higher than those in non-IBS group （22.9% vs. 9.6%, 26.6% vs. 12.4%, P 〈 0.05 ）. Score of SAS and SDS in IBS group were significantly higher than those in non-IBS group （50.86 ± 7.27 vs. 36.54 ± 6.97, 53.47 ± 7.86 vs. 38.25 ± 9.83, P 〈 0.05）. Positive correlation was found between score of SAS and SDS and stress factors such as feeling lonely, depression, intensive training, working pressure, poor relationship with colleagues, solving emergency event or participating in military exercises in IBS group （ P 〈 0.05 ）. Conclusions ： IBS in soldiers is related with stress and psychological factors.