双手搐搦-低钙血症-肌酶升高

Carpal spasms-hypocalcemia-elevated serum creatine kinase

低钙性肌病是甲状旁腺功能减退症(以下简称甲旁减)的罕见并发症之一。本文报道了1例特发性甲旁减导致肌酸激酶(creatine kinase,CK)升高。患者为23岁男性,因间断双手搐搦10年入院,入院前2个月有一次癫痫样发作,实验室检查示血钙和甲状旁腺素水平降低,血清CK水平明显升高,给予钙剂及维生素D补充治疗后,随血钙水平上升,CK逐渐下降。本文同时对甲旁减合并肌酶升高的相关文献进行了复习和总结。

Hypocalcemic myopathy is a rare manifestation of hypoparathyroidism. Here we reported a case of hypocalcemia due to idiopathic hypoparathyroidism associated with elevated serum creatine kinase level. A 23-year-old man suffered from intermittent carpal spasms for 10 years and he had seizure 2 months before the hospitalization. Laboratory tests showed decreased serum calcium and parathyroid hormone levels accompanied with increased serum creatine kinase concentration. With the treatment with calcium and vitamin D supplementation,the serum creatine kinase levels decreased gradually accompanied by the improvement of hypocalcemia. The related literature was reviewed.