白云鄂博儿童尿中镧、铈、钕含量参比值的研究

Reference Value for Lanthanum,Cerium and Neodymium in Children Urine in Bayan Obo

目的了解包头市白云鄂博健康儿童体内轻稀土元素的暴露水平,确定白云鄂博儿童尿中镧、铈、钕参比值。方法按照分层抽样法采集白云鄂博144名健康小学生晨尿,选择其中肌酐浓度在正常范围的123人,用ICP-MS测定尿中镧、铈、钕的含量,结果经肌酐校正后,制定95%参考值上限。结果本次调查的尿中镧、铈、钕含量呈对数正态分布,性别和各年龄组间差异均无统计学意义(P>0.05)。结论初步确定白云鄂博儿童尿中轻稀土元素含量参比值分别为镧<72.542μg/g,铈<75.818μg/g,钕<45.595μg/g。

Objective To survey the exposure of light rare earth elements in healthy children and to determine the reference value for lanthanum,cerium and neodymium in the urine of children in Bayan Obo. Methods Morning urine samples from 144 healthy pupils in Baotou Bayan Obo were collected,and the content of lanthanum,cerium and neodymium in 123 urine samples with normal creatinine in urine were determined by ICP-MS. The results were corrected by urinary creatinine and the 95% upper limit was calculated as the reference value. Results The concentration of lanthanum,cerium and neodymium in urine samples showed a lognormal distribution. The differences between genders and in different age groups were not statistically significant（ P〉 0. 05）. Conclusions The reference value for the concentration of lanthanum,cerium and neodymium in morning urine of children in Bayan Obo district was less than 72. 542,75. 818 and 45. 595 μg / g,respectively