超激光星状神经节照射对头面颈肩部带状疱疹疗效分析

Effect of super laser irradiating stellate ganglion on head,face,neck and shoulder herpes zoster

目的观察超激光星状神经节照射对头面颈肩部带状疱疹的疗效。方法将头面颈肩部带状疱疹患者53例随机分为对照组与观察组。对照组给予抗病毒、镇痛、营养神经及超激光皮损部位照射治疗。观察组在对照组治疗基础上加用超激光星状神经节照射治疗。评价皮损结痂、疼痛情况,对比两组临床疗效及治疗前后血IL-6、IL-10及IL-2水平。结果两组患者均在治疗3~4d疼痛开始缓解,皮损结痂。观察组疼痛基本消失时间为（5.8±1.03）d,短于对照组,差异有统计学意义（P〈0.05）。对照组总有效率为71%,观察组总有效率为84%,观察组总体疗效优于对照组。治疗后1周、1个月、3个月观察组疼痛数字评价量表（numerical rating scale,NRS）评分均低于对照组（P〈0.05）。治疗后两组IL-6、IL-10水平降低,IL-2水平升高。治疗后观察组IL-6、IL-10水平低于对照组,IL-2高于对照组（P〈0.05）。结论在抗病毒、营养神经、镇痛及局部激光照射基础上加用星状神经节超激光照射治疗可有效缓解疼痛、提高疗效、改善免疫。

Objective To observe the effect of super laser irradiating stellate ganglion on head, face, neck and shoulder herpes zoster. Methods Fifty-three patients with head, face, neck and shoulder herpes zoster were randomly divided into control group and observation group. Patients in control group received antiviral, analgesic, neurotrophic and local skin super laser illumination treatment. Patients in observation group were treated with stellate ganglion super laser irradiation based on treatment methods of control group. The incrustation time and pain relief condition were evaluated. Before and after treatment , the serum IL-6, IL-10 and IL-2 levels were measured and compared. Results Three or four days after treatment, the pain began to relieve and skin began to form the scab in two groups. In observation group , the pain totally relief time was shorter than control group. In control group, the total effective rate was 71%. It was higher in observation group reaching to 84%. One week, one month and three months after treatment, the numerical rating scale （NRS） were lower in observation group. After treatment, IL-6, IL-10 reduced and IL-2 elevated in both groups. After treatment, in observation group IL-6, IL-10 were lower and IL-2 was higher than control group （P〈0.05）. Conclusion On the base of anti-virus, nutrition nerve, analgesia and local laser irradiation, therapy of super laser irradiate stellate ganglion can relieve pain, improve curative effect and immunity.