摘要
肺癌是世界上最常见的恶性肿瘤之一,其中小细胞肺癌发生率约15%。小细胞肺癌对一线化疗高度敏感,但多数患者在一线治疗缓解后很快出现复发进展,因此,自20世纪80年代起已开展不少小细胞肺癌维持治疗的相关临床研究,涉及到化疗药物、生物制剂及分子靶向药物。但其结果仍存在争论,现对该方面内容综述如下。
Lung cancer is one of the common malignant tumors in the world, the incidence of small cell lung cancer is about 15% among them. Small ceU lung cancer is highly sensitive to first-line chemotherapy3 but most of the patients relapse after the first-line therapy quickly. Despitemany clinical researchof chemotherapy, biological agents and molecular targeting agents since the 1980s, there still remains a substantial lack of consensus regarding the appropriate therapeutic management on maintenance therapy of small cell lung cancer. The review focuses on maintenance therapy of small cell lung cancer.
出处
《中国肺癌杂志》
CAS
CSCD
北大核心
2015年第9期559-564,共6页
Chinese Journal of Lung Cancer
关键词
肺肿瘤
维持治疗
化疗
Lung neoplasms
Maintenance therapy
Chemotherapy