中西医结合治疗急性痛风性关节炎疗效的Meta分析

A Meta-analysis of Literature on the Efficacy of Combined Chinese and Western Medicine in the Treatment of Acute Gout Arthritis

目的:通过检索文献探讨运用中西医结合和西药治疗急性痛风性关节炎的疗效。方法:检索2010年1月至2015年5月中国知网(CNKI)、维普网(VIP)中关于中西医结合治疗急性痛风性关节炎的随机对照试验研究文献,对所有符合纳入标准的文献进行Jadad质量标准评分,纳入符合标准的文献共24篇,运用Review Manager 5.1统计软件进行Meta分析。结果:异质性检验:χ2=37.84,I2=39%<50%,异质性检验差异无统计学意义(P>0.05),具有同质性;合并效应量统计RR=1.21>1,95%CI=[1.17,1.25]>1,Z=10.84(P<0.000 01),因此认为中西医结合治疗组和西药对照组疗效比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗急性痛风性关节炎疗效优于西药。

Objective：To investigate the clinical effect of treating acute gout arthritis with combined Chinese and Western medicine or Western medicine.Methods：Literature from January 2010 to May 2015 on the treatment of acute gout arthritis with combined Chinese and Western medicine was searched from the websites of CNKI and VIP.24 essays were chosen to make a quality score with Jadad rating scales and make a meta-analysis with statistical software Review Manager 5.1.Results：Test for heterogeneity was χ^2 = 37.84,I^2 = 39%〈 50%,the difference of which had no statistical significance.The combined effect size statistics was RR = 1.21 1,95%CI =[1.17,1.25] 〉1,Z = 10.84（P〈0.000 01）.Therefore,the difference of curative effects between traditional Chinese medicine and Western medicine was statistically significant（P〈0.05）.Conclusion：Treating acute gout arthritis with combined Chinese and Western medicine has a better clinical efficacy than that of the control group with Western medicine.